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WATCH: Woman with cancer has ‘no evidence of disease’ after life-changing transplant

Amy Piccioli was diagnosed with stage 4 colorectal cancer at the age of 39.

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Major heat wave slams SoCal. Record-breaking temperatures seen in Ventura County

A major heat wave kicked off in the Southland, where temperatures are predicted to soar 25 degrees above normal, smash records across L.A. and bring a high risk of heat-related illness.

WATCH: Sneak-peak at the performances at the Oscars

"GMA's" Lara Spencer spoke with Mandy Moore, an Emmy award-winning choreographer, for a preview of the big performances at the Oscars.

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WATCH: Shelter rescues kitten who appeared inflated like a balloon

ABC News' Danny New speaks to a veterinarian who believes the condition was caused by damage to the cat's windpipe.

WATCH: No deal in Homeland Security shutdown talks

Travelers looking to escape for spring break are encountering long security lines and more widespread travel problems as the latest partial government shutdown drags on.